Exosomes are small extracellular vesicles secreted by cells that play crucial roles in intercellular communication and various physiological processes. Lyophilization is a service/method used to remove water from biological samples while preserving their structure and function. Exosome lyophilization refers to the process of freeze-drying exosomes for long-term preservation and storage. During exosome lyophilization, samples are […]
Glossary
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Author: learncatachem
Ethylene glycol diagnostics
Ethylene glycol is a toxic substance commonly found in antifreeze, brake fluid, and other industrial products. Accidental or intentional ingestion of ethylene glycol can lead to severe poisoning and potentially fatal consequences. Ethylene glycol diagnostics refer to tests and methods used to detect and diagnose ethylene glycol poisoning. Diagnostic methods for ethylene glycol poisoning typically […]
Does Lyophilization Degrade RNA?
Lyophilization is commonly used to preserve biological materials such as proteins, enzymes, vaccines, and other biomolecules including RNA. While lyophilization can be beneficial for long-term storage of RNA by removing water and preventing degradation from enzymatic activity, it can also potentially cause damage to RNA molecules if not performed properly. To minimize RNA degradation during […]
Diagnostic Reagents
Diagnostic reagents are essential components of diagnostic tests used in medical settings to detect specific analytes or markers in biological samples. These reagents encompass a range of types, including chemical, immunological, nucleic acid, microbiological, and molecular probes. Chemical reagents undergo reactions with analytes to produce detectable signals, while immunological reagents rely on antigen-antibody interactions. Nucleic […]
Custom Lyophilization
Custom lyophilization refers to the process of freeze-drying a substance according to specific customer requirements or preferences. Lyophilization is a dehydration process commonly used in various industries, including diagnostics and biotechnology, to preserve perishable materials or substances. During lyophilization, the substance is first frozen and then subjected to vacuum conditions, causing the frozen water (or […]
Creatine Kinase Reagents
Creatine kinase (CK) reagents are substances or kits used in laboratory assays to measure the activity of creatine kinase enzymes in biological samples. Creatine kinase is an enzyme found predominantly in tissues with high energy demands, such as skeletal muscle, heart muscle, and brain tissue. It plays a crucial role in the generation of adenosine […]
Canine albumin
Canine albumin refers to the albumin protein found in the blood of dogs. Albumin is a globular protein produced primarily by the liver and serves various essential functions in the body, including maintaining colloidal osmotic pressure, transporting hormones, fatty acids, and other substances, and contributing to the regulation of blood pH. In dogs, as in […]
Calcium Arsenazo
Calcium arsenazo is a chemical compound often used in analytical chemistry for the detection and quantification of calcium ions (Ca^2+) in aqueous solutions. It belongs to a class of compounds known as arsenazo dyes, which are characterized by their ability to form stable complexes with metal ions, resulting in color changes that can be detected […]
Monoclonal Antibodies
Monoclonal antibodies (mAbs) are laboratory-produced molecules that are designed to mimic the immune system’s ability to target and neutralize specific substances, such as pathogens or abnormal cells. They are called “monoclonal” because they are derived from a single clone of cells, typically hybridoma cells created by fusing antibody-producing B cells with immortalized myeloma cells. This […]
Antigens
Antigens are molecules or substances that are recognized by the immune system as foreign or non-self. These can include proteins, polysaccharides, glycoproteins, and other molecular structures present on the surface of pathogens such as bacteria, viruses, fungi, or parasites. Antigens can also be found on the surface of transplanted tissues or cells from another organism. […]