Biotech Terms Glossary.

Glossary

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Liquid Culture Lyophilization

“Liquid culture lyophilization” is the process of freeze-drying a liquid culture to preserve microbial cells or other biological material.

In microbiology and biotechnology, liquid cultures are commonly used to grow and maintain microorganisms such as bacteria, yeast, or fungi in a liquid medium. These cultures are often used for various purposes such as research, industrial production of biochemicals, or medical applications.

Lyophilization is a biotech term- it’s a method used to remove water from a sample while preserving its structure and biological activity. In the context of liquid cultures, lyophilization involves freezing the culture and then subjecting it to vacuum conditions, causing the frozen water to sublime directly from the solid phase to the gas phase. This process effectively removes water from the sample without damaging the biological material.

Liquid culture lyophilization is commonly employed to preserve microbial cultures for long-term storage. By removing water from the liquid culture, lyophilization stabilizes the microbial cells, enzymes, or other biological components, preventing degradation and extending the shelf-life of the culture. This preservation method allows researchers and industries to store microbial cultures in a stable state, ready for rehydration and use when needed.