Lyophilized glucagon, a vital pharmaceutical compound, is a lyophilized (freeze-dried) formulation of the peptide hormone glucagon. Glucagon, synthesized by the alpha cells of the pancreas, plays an important role in glucose homeostasis by stimulating glycogenolysis and gluconeogenesis in the liver, thereby increasing blood glucose levels. Lyophilization is employed in the manufacturing process to enhance the stability and shelf-life of the product. This process involves freezing the solution containing glucagon under vacuum, followed by sublimation of ice to remove water, leaving behind a dry powder. This dry form mitigates the risk of degradation or denaturation of the protein, ensuring the preservation of its biological activity.
Glossary
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