Lyophilization, scientifically termed freeze-drying, is a meticulous dehydration technique employed predominantly in the preservation of delicate biological entities and bio-pharma formulations. This method entails subjecting the material to be desiccated to frigid temperatures, inducing freezing, followed by the application of reduced pressure to facilitate sublimation—a phase transition from solid to gas—of the entrapped water molecules. The resultant desiccated product manifests minimal structural compromise and retains its biochemical integrity, rendering it amenable to prolonged storage sans refrigeration, with the potential for facile reconstitution.
Across diverse disciplines, including pharmaceuticals, biotechnology, and food science, lyophilization stands as a quintessential process for the stabilization and long-term storage of moisture-sensitive compounds.
Catachem offers lyophilization services to preserve delicate substances like biologics, nucleic acids, enzymes, proteins, calibrators and controls.